A protocol is a plan or set of steps to which a study will adhere. A protocol for a systematic review should describe:
- The rationale for the review
- The objectives of the review
- The methods that will be used to locate, select, and critically appraise studies
- The methods that will be used to analyze data from the included studies
Development of a protocol is necessary because it promotes transparency, helps reduce the potential for bias, and serves to avoid unintended duplication of reviews.
Consult Cochrane Interactive Learning Module 2: Writing the Review Protocol for further information. *Please note you will need to register for a Cochrane account while initially on the Mayo network. You'll receive an email message containing a link to create a password and activate your account.*