Sherrington, Charles S. The integrative action of the nervous system. New York, Charles Scribner’s Sons, 1906.
In this classic of modern neurology, Sherrington summed up his years of experiments and observations on the nervous system and the reflexes and developed a theory that has had a far-reaching and profound influence on modern neurophysiology and clinical neurology. Briefly, his theory was that the nervous system acts as the coordinator of various parts of the body and that the reflexes are the simplest expressions of the integrative action of the nervous system, enabling the entire body to function toward one definite end at a time. Sherrington shared the Nobel prize for medicine and physiology in 1932 with Edgar Douglas Adrian, for their work on the nervous system.