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Chordomas and Chondrosarcomas of the Skull Base and Spine by
Chordomas and Chondrosarcomas of the Skull Base and Spine, Second Edition, is a major reference and guide for neurosurgeons, medical oncologists, neuroscientists, orthopedic surgeons, head and neck surgeons and radiation oncologists that treat patients and research chordomas and chondrosarcomas of the axial skeleton. This book is the unique result of the collaboration of multidisciplinary specialists from a wide variety of fields (neurological sciences, medical oncology, molecular biology, orthopedics and radiation oncology), offering the most relevant information about chordomas and chondrosarcomas of the axial skeleton from each of these fields condensed into one single volume. It contains new medical knowledge and scientific advances regarding the treatment of these types of tumors. Additionally, the book includes chapters written by the Chordoma Foundation and Sarcoma Foundation of America, providing the most valuable information and support for patients and their relatives.
Comprehensive Management of Skull Base Tumors by
The consummate guide on the contemporary management of complex skull base tumors from renowned multidisciplinary experts! An increased understanding of the biology and molecular characterization of skull base tumors has led to innovative new approaches. Endoscopic tumor resection, surgical reconstruction, and advances in radiation delivery, chemotherapy, and targeted biologic therapy, have greatly expanded treatment options for patients with these challenging tumors. The updated second edition of Comprehensive Management of Skull Base Tumors by master surgeons Ehab Hanna, Franco DeMonte, and an impressive group of global experts reflects expanded knowledge of skull base tumors and evidence-based advances. This generously illustrated second edition is organized into three sections with 42 chapters. Section I features expanded coverage of endonasal skull base anatomy and surgical principles, as well as radiotherapeutic advances such as proton therapy and stereotactic radiation. Section II is focused on site-specific procedures with emphasis on surgical approaches, and Section III focuses on tumor-specific considerations with emphasis on multidisciplinary treatment approaches. Core topics of this thorough book include pathology, genetics, diagnostic considerations, surgical reconstruction, rehabilitation, chemotherapy, functional outcomes, quality of life issues, neurocognitive assessment, and cerebrovascular management. Key Features In-depth discussion of anatomic regions of the cranial base, including surgical anatomy, regional pathology, differential diagnosis, clinical assessment, diagnostic imaging, and surgical approaches Incidence, epidemiology, pathology, staging, multidisciplinary treatment, outcome, and prognosis for a wide range of neoplasms including squamous cell carcinoma, chondrosarcomas, chordomas, meningiomas, schwannomas, paragangliomas, pituitary adenomas, craniopharyngiomas, epidermoids, and fibro-osseous lesions Outstanding illustrations, surgical and clinical photos, imaging, tables, and videos new to this edition, enhance understanding of complex skull base tumors The most comprehensive resource available today on the management and treatment of skull base tumors, this book is essential reading for neurosurgical and otolaryngology residents. It will also benefit surgeons who specialize in oromaxillofacial, craniofacial, and plastic and reconstructive surgery. This book includes complimentary access to a digital copy on https://medone.thieme.com.
Fluorescence-Guided Neurosurgery: Neuro-oncology and Cerebrovascular Applications by
The definitive textbook on state-of-the-art fluorescence-guided neurosurgery Advances in fluorescence-guided surgery (FGS) have resulted in a paradigm shift in neurosurgical approaches to neuro-oncological and cerebrovascular pathologies. Edited by two of the foremost authorities on the topic, Fluorescence-Guided Neurosurgery: Neuro-oncology and Cerebrovascular Applications encompasses the depth and breadth of this groundbreaking, still nascent technology. The book reflects significant contributions made by world renowned neurosurgeons Constantinos Hadjipanayis, Walter Stummer, and esteemed contributors on the growing uses of 5-aminolevulinic acid (5-ALA) and other FGS agents. The European Medicine Agency approved 5-ALA in 2007, heralding the birth of FGS globally. In 2017, the U.S. Food and Drug Administration approved 5-ALA (Gleolan) as an imaging agent to facilitate realtime detection and visualization of malignant tissue during glioma surgery. In the two decades since Dr. Stummer's initial description of 5-ALA FGS in a human patient, major strides have been made in its practical applications, leading to improved resection outcomes. As FGS is increasingly incorporated into neurosurgical practice, it holds promise for future innovations. Generously-illustrated and enhanced with online videos, this textbook is the definitive resource on the subject. Key Features The improved efficacy of 5-ALA for resecting high- and low-grade gliomas, recurrences, meningiomas, brain metastases, spinal cord tumors, pediatric brain tumors, and other adult tumors The future of fluorescence, including potentially powerful new fluorophores molecularly targeted specifically to tumors The use of the fluorescent agent indocyanine green (ICG) for brain tumors, cerebral aneurysms, AVMs, and cerebral vascularization Special topics such as fluorescein, illuminating tumor paint, confocal
Getting Ready for Brain Tumor Surgery by
Gain confidence in acquiring basic manual skills for brain tumor surgery... In training to become a neurosurgeon, many of the crucial manual skills that must be acquired can only be mastered through growing experience during the rigorous and lengthy training process. Yet, many - often essential - practical skills can quickly be learned, practiced, and even mastered, away from the OR. The author's motivation for writing this guide arose during his own training and his need for just such a practical aid. Getting Ready for Brain Tumor Surgery provides the readers with a basic set of exercises that will allow him to develop and improve their motor skills, handling of various tissues, and general technical competence. Detailed instructions are given in the illustrated text and in accompanying videos. Topics include: Planning: visualization of the procedure The craniotomy - using a coconut Working with the microscope Removing a gyrus: subpial resection Removing a brain tumor using an artificial model Microsurgical training: the chicken wing model Junior neurosurgical residents and interns will benefit greatly from this handy guide.
Clinically focused and designed to provide a to-the-point overview, Glioblastoma, by Drs. Steven Brem and Kalil G. Abdullah, brings you up to date with increased understanding, new treatment protocols, and recent advances in the field. Written by contributing specialists who are global experts in their respective areas, this one-stop reference provides neurosurgeons, medical-and-radiation oncologists, neuro-oncologists, neuropathologists, internal medicine physicians, and researchers with a dependable source of information on current treatment options, tumor recurrence, and patient care. Evidence for current treatment options for de novo and recurrent glioblastoma, indications for local and topical therapies, immunotherapy, gene therapy, nanotherapy, small-molecule inhibition, electric tumor treating field stimulation, and antiangiogenic therapies and the role of Avastin. Recent advances relating to tumor resection, such as stereotactic laser ablation, diffusion tensor imaging, and fluorescent markers. Prognostic molecular and genetic markers and the impact of gene mutations on survival, as well as controversies relating to pseudo-progression. Lessons learned from unsuccessful interventions, as well as the most promising aspects of future glioblastoma research and treatment. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Meningiomas of the Skull Base by
A comprehensive overview of the contemporary management of skull base meningiomas Meningiomas, the second most frequent of intracranial tumors, are characterized by a protean range of possible locations and appearances, due to their origin from the extensive and intricately formed meninges. As such, a wide variety of differential diagnoses is typical, and the therapies chosen are necessarily highly variable. The introductory chapters of this book cover the pathology of these tumors, the evolution of special surgical methods, instrumentation, intraoperative monitoring, and the role of radiosurgery. Ten surgical chapters cover the individual regions of occurrence, including the sphenoid wing, olfactory groove, cerebellopontine angle, etc., all of which require a specialized approach and therapeutic strategy. Key Features: Discussion of pathology and therapy organized by anatomic location of the lesions with the goal of providing best patient outcomes New WHO meningioma classification system based on most recent research in growth patterns, gene sequencing, and molecular patterns of development Important updates on the newest developments in treatment modalities for meningioma, including the lesser invasive radiotherapy and radiosurgery for the smaller lesions and to avoid the necessity of performing radical surgery Meningiomas of the Skull Base: Treatment Nuances in Contemporary Neurosurgery is an essential reference guide for neurosurgeons and neurologists (in training and in practice) and will also be welcomed by skull base surgeons and otolaryngologists. This book includes complimentary access to a digital copy on https://medone.thieme.com.