Chimeric Antigen Receptor T-Cell Therapies for Cancer by Daniel W. Lee; Nirali N. Shah, 2020From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells in a concise and practical format. Providing authoritative guidance on the implementation and management of CAR T-cell therapy from Drs. Daniel W. Lee and Nirali N. Shah, this clinical resource keeps you up to date on the latest developments in this rapidly evolving area. Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging therapy, post-CAR monitoring, and multidisciplinary approaches to supportive care. Includes key topics on associated toxicities such as predictive biomarkers, infections, and multidisciplinary approaches to supportive care. Presents current knowledge on FDA approved CAR T-cell products as well as developments on the horizon. Editors and authors represent leading investigators in academia and worldwide pioneers of CAR therapy.
ISBN: 9780323661812
Publication Date: 2019-12-02
Clinical Immuno-Oncology by John E. Niederhuber, 2024There is no other more rapidly advancing and therefore promising field in cancer treatment than immuno-oncology. Today, we have a much greater and, in fact, continually expanding understanding of the complex relationships existing between the host’s tissues, the host immune system, the tumor, and the tumor microenvironment as these entities relate to the process of tumor initiation and tumor progression. The goal of this book is to enable its readers—those caring for patients with cancer no matter their specialty—to achieve a greater in-depth understanding of these relationships and how they can be engineered to drive the immune system to effectively treat the cancer. It is hoped that this text will enable the trainee and the practicing oncologist to acquire the language of immunology and, in so doing, facilitate the more purposeful reading of the rapidly evolving clinical immuno-oncology literature. Empowered by this knowledge, it is hoped that practitioners will be optimally prepared to discuss and apply immunotherapies in translational research and in the actual care of their patients.
ISBN: 9780323877633
eBooks
Translational Immunotherapy of Brain Tumors by John H. Sampson, 2017Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. 2018 BMA Medical Book Awards Highly Commended in Oncology